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If you are also taking a beta-blocker such as betapace, coreg, corgard, dutoprol, inderal, innopran, lopressor, normodyne, tenormin, tenoretic, toprol, trandate, and others , do not suddenly stop using the beta blocker without first talking to your doctor.

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Tell your doctor if you are sick with severe vomiting or diarrheaor if you are sweating more than usualProlonged illness can lead to a serious electrolyte imbalancemaking it dangerous for you to use sotalol.

Sotalol is a beta-adrenergic blocking drug that is used to treat abnormal heart rhythmsSotalol is a first generation beta blocker in a class that includes propranololInderalInnoPrannadololCorgardpenbutolol sulfateLevatoltimololBlocadrenand pindololViskenThese drugs differ from other beta blocking drugs because they are non-selective in naturemeaning that they block both beta-1 and beta-2 receptors on nerves andthereforewill affect not only the heart but also the kidneyslungsgastrointestinal tractliveruterusmuscles surrounding blood vesselsand skeletal muscleNorepinephrine and epinephrineadrenalineare chemicals released within the body that attach to receptors on several types of cellsincluding nerves and some musclesAttachment changes the way the cells functioneither stimulating the cells or suppressing themin part through beta receptorsSotalol prevents norepinephrine and epinephrine from binding to beta receptors on nervesBy blocking the effect of norepinephrine and epinephrinebeta blockers reduce heart ratereduce the force of the heart’s contractionsand reduce blood pressure by relaxing the muscles surrounding the blood vesselsSotalol also directly reduces the rate at which the heart beats by reducing the rapidity of firing of the normal generator of electrical impulses in the heartthe heart’s pacemakerThe FDA approved sotalol in October1992.

This is not a complete list of possible side effectsIf you notice other effects not listed abovecontact your doctor or pharmacist.

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heart rhythm disorder, especially if you take quinidine quin-g , disopyramide norpace , bretylium bretylol , procainamide pronestyl, procan sr , amiodarone cordarone, pacerone , or sotalol betapace ; a history of allergic reaction to an antibiotic; muscle weakness or trouble breathing; joint problems; kidney or liver disease; epilepsy or a history of seizures; diabetes; low levels of potassium in your blood hypokalemia ; or a personal or family history of long qt syndrome.

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