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Carafate can make it harder for your body to absorb other medications you take by mouthAvoid taking any other medications within 2 hours before or after you take sucralfate.
Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorptionbioavailabilityof single doses of the followingcimetidinedigoxinfluoroquinolone antibioticsketoconazolel-thyroxinephenytoinquinidineranitidinetetracyclineand theophyllineSubtherapeutic prothrombin times with concomitant warfarin and sucralfate therapy have been reported in spontaneous and published case reportsHowevertwo clinical studies have demonstrated no change in either serum warfarin concentration or prothrombin time with the addition of sucralfate to chronic warfarin therapyThe mechanism of these interactions appears to be nonsystemic in naturepresumably resulting from sucralfate binding to the concomitant agent in the gastrointestinal tractIn all cases studied to datecimetidineciprofloxacindigoxinnorfloxacinofloxacinand ranitidinedosing the concomitant medication 2 hours before sucralfate eliminated the interactionDue to CARAFATE Oral Suspension’s potential to alter the absorption of some drugsCARAFATE Oral Suspension should be administered separately from other drugs when alterations in bioavailability are felt to be criticalIn these casespatients should be monitored appropriately.
It is not known whether sucralfate passes into breast milk or if it could harm a nursing babyTell your doctor if you are breast-feeding a baby.
Before using this medicationtell your doctor or pharmacist your medical historyespecially ofkidney problemsswallowing problemssuch as difficulty swallowinghistory of aspirationstomach/intestine problemse.gdelayed gastric emptyingtube feedinguse of a breathing tubetracheotomy
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