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If you are taking this medication to treat symptoms due to familial Mediterranean fevertell your doctor if your condition does not improve or if it worsens.

Patients with both renal and hepatic impairment should not be given colchicine capsules.

About all of your medical conditions if you have kidney or liver problems if you are pregnant or plan to become pregnantIt is not known if colchicine capsules can harm your unborn babyTalk to your healthcare provider if you are pregnant or plan to become pregnantif you are breastfeeding or plan to breastfeedColchicine can pass into your breast milk and may harm your babyTalk to your healthcare provider about the best way to feed your baby if you take colchicine capsules.

The following reactions have been reported with colchicineThese have been generally reversible by interrupting treatment or lowering the dose of colchicine:

Case reports and epidemiology studies in human male subjects on colchicine therapy indicate that infertility from colchicine is rareA case report indicated that azoospermia was reversed when therapy was stoppedCase reports and epidemiology studies in female subjects on colchicine therapy have not established a clear relationship between colchicine use and female infertility.

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the treatment combination demonstrated superior results over colchicine alone in the treatment of primary amyloidosis.

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