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Yet helen whitehead is not alone in experiencing a serious reaction to lariam that she says has blighted her life.

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If you vomit within 1 hour after taking this medicationtake another half doseIf your vomiting continuescall your doctor.

Tell your doctorpharmacistor nurse if you are takinghave recently taken or might take any other medicines including:

Clinical studies of Lariammefloquinedid not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjectsOther reported clinical experience has not identified differences in responses between the elderly and younger patientsSince electrocardiographic abnormalities have been observed in individuals treated with Lariammefloquinesee PRECAUTIONSand underlying cardiac disease is more prevalent in elderly than in younger patientsthe benefits of Lariammefloquinetherapy should be weighed against the possibility of adverse cardiac effects in elderly patients.

In patients with impaired liver function the elimination of mefloquine may be prolongedleading to higher plasma levels.

During long-term prophylaxis2 yearsthe trough concentrations and the elimination half-life of mefloquine were similar to those obtained in the same population after 6 months of drug usewhich is when they reached steady state.

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because of the long half-life of mefloquine, adverse reactions to lariam may occur or persist up to several weeks after discontinuation of the drug.

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