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In addition, co-administration of promethazine with haloperidol may increase the risk of adverse effects such as drowsiness, dizziness, orthostatic hypotension, anticholinergic effects, extrapyramidal symptoms, neuroleptic malignant syndrome, or seizures.

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Oral25 mg orally onceThis dose may be repeated every 4 hours as needed.

Promethazine should not be given to a child younger than 2 years oldPromethazine can cause severe breathing problems or death in very young childrenCarefully follow your doctor’s instructions when giving this medicine to a child of any age.

Promethazine is in a group of drugs called phenothiazinesFEEN-oh-THYE-a-zeensIt works by changing the actions of chemicals in your brainPromethazine also acts as an antihistamineIt blocks the effects of the naturally occurring chemical histamine in your body.

Promethazine can be administered by mouth in tablet or syrupliquidformby injectionintravenouslyor into the rectum in the form of a suppositoryWhen taking liquid promethazinepatients should use a measuring spoon or cup made specifically for measuring medicationsand not a household spoonThe suppository can only be inserted through the rectumlower part of the large intestine through the anusand should not be swallowed.

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