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Serum levels drawn within 6-8 hours of dose will be falsely high because of prolonged distribution phase.

Heart failure patients with preserved ventricular function including acute cor pulmonaleamyloid heart diseaseand constrictive pericarditis may be susceptible to digoxin toxicity.

Do not switch between different PO forms or between brand and generic forms of digoxinbioavailability varies.

Avoid becoming overheated or dehydrated during exercisein hot weatheror by not drinking enough fluidsDigoxin overdose can occur more easily if you are dehydrated.

Keep taking digoxin as directedeven if you feel wellGet your prescription refilled before you run out of medicine completely.

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alpha-glucosidase inhibitors moderate acarbose, an alpha-glucosidase inhibitor, has been found to decrease the mean bioavailability auc of digoxin by 16 90 confidence interval range 8-23 , decrease the mean cmax of digoxin by 26 90 confidence interval range 16-34 , and decrease the mean trough concentration of digoxin by 9 90 confidence limit 19 decrease to 2 increase .

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